s1 subunit vaccine strain omicron variant spike proteins Search Results


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GenScript corporation s1 subunit vaccine strain omicron variant spike proteins
IFN-γ ELIspot assay was performed with overlapping spike peptide pools from ( A ) vaccine strain and ( B ) <t>S1</t> <t>spike</t> <t>proteins</t> from vaccine strain or Omicron variant in VR21, VR26, and VR37 1–3 weeks after boost in A; in VR37 and VR97 1–3 weeks after boost in B; and in breakthrough VRs. IFN-γ spot-forming units (SFU) per million PBMCs are shown. Orange diamonds represent VR21, VR26, VR37, and VR97 at the breakthrough time point. Statistical comparisons were done using ordinary 1-way ANOVA (unpaired) and Holm-Šidák’s multiple comparison test, with a single pool variance used. * P =0.0332, ** P =0.0021.
S1 Subunit Vaccine Strain Omicron Variant Spike Proteins, supplied by GenScript corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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IFN-γ ELIspot assay was performed with overlapping spike peptide pools from ( A ) vaccine strain and ( B ) S1 spike proteins from vaccine strain or Omicron variant in VR21, VR26, and VR37 1–3 weeks after boost in A; in VR37 and VR97 1–3 weeks after boost in B; and in breakthrough VRs. IFN-γ spot-forming units (SFU) per million PBMCs are shown. Orange diamonds represent VR21, VR26, VR37, and VR97 at the breakthrough time point. Statistical comparisons were done using ordinary 1-way ANOVA (unpaired) and Holm-Šidák’s multiple comparison test, with a single pool variance used. * P =0.0332, ** P =0.0021.

Journal: JCI Insight

Article Title: SARS-CoV-2–specific immune responses in boosted vaccine recipients with breakthrough infections during the Omicron variant surge

doi: 10.1172/jci.insight.159474

Figure Lengend Snippet: IFN-γ ELIspot assay was performed with overlapping spike peptide pools from ( A ) vaccine strain and ( B ) S1 spike proteins from vaccine strain or Omicron variant in VR21, VR26, and VR37 1–3 weeks after boost in A; in VR37 and VR97 1–3 weeks after boost in B; and in breakthrough VRs. IFN-γ spot-forming units (SFU) per million PBMCs are shown. Orange diamonds represent VR21, VR26, VR37, and VR97 at the breakthrough time point. Statistical comparisons were done using ordinary 1-way ANOVA (unpaired) and Holm-Šidák’s multiple comparison test, with a single pool variance used. * P =0.0332, ** P =0.0021.

Article Snippet: The IFN-γ ELISpot assay was used to analyze T cell responses to SARS-CoV-2 spike and nucleocapsid peptide pools (BEI Resources) and the S1 subunit of the vaccine strain and Omicron variant spike proteins (Genscript Biotech Corporation).

Techniques: Enzyme-linked Immunospot, Variant Assay, Comparison